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Microwell Arrays as a Platform for Discovery and Diagnostics
4th May @ 12:00 pm - 1:00 pm
We have developed microwell arrays as a platform for both fundamental discovery and bioanalytical measurements. The microwells can be used as miniature reaction chambers to observe the kinetics of billions of individual molecules to screen for activities that cannot be detected using bulk measurements. The arrays can also be used to measure the concentrations of proteins and nucleic acids more than a thousand times lower than traditional assays. This ultrasensitivity provides the ability to measure molecules in biological samples, such as blood, at levels that cannot be measured using conventional methods. The translation of these technologies from the laboratory to the commercial sector as well as to the clinic will also be described.